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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7185fe510bd88011a11556991c064f6fa02688ed70aa32a8886c4942c11560c4' 
  AND token = '5tjZm2uUpWM5hBS5aNd977euTLxJIJHaUaAYlUiuuPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}