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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db78a340bba2b704526f53f0ade380bf17f25b729dca699f5d1c0b463a40db6b' 
  AND token = '8mmGpZiB/wfEF0wDBLrq6LARIrH7ojTW0ebvjqjUKco=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}