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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e980cb1b0ab28c995582a599deb55f00eaf4ab813149b3a73dc4cd091eee31a1' 
  AND token = 'QXMScLawfm/Ft3zHMj7jxr76o8Cj2gKs/lKg19HWbSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}