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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06df0e00bf738e409017d602074a707ebd4c242a4cc24824f3e0403af58a6695' 
  AND token = '8xUazOCVlzqFBYgRhewHA2RwIEwkvPBo0gGFN89B3P0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}