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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccb32bd6c8f31ff5d7b20f0333bb55e05e540e8a4aab8e43d601d56646140d13' 
  AND token = '4S1U4/N2Z07mSCbhFo9bUYphR1MXkM3auCNQ5AxLEyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}