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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c874408098ce9f75ad503e6e484bc91f716feb4c9c4e3a095957a96734cef97' 
  AND token = 'xJMScGrMyAZC6yChXJbf6A7q3fqNhTiPt0PtTU3/OnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}