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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1e9d0f9cc9050bc02e34153b271d18f002c489ed74a9e2a3afc08ddfd9386da' 
  AND token = 'qYQpRIGxi5CoPtGbmJk0WWGRHeO9XL2PHl4uJrh2QvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}