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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8b9fe2344644214ecd397704df33f5f8cf5d894ef62ae121b79d0794dc49c93' 
  AND token = '2G5o/RlDMoM1mWe0q8kmisRVtS1tqV78tE7QIyB+qdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}