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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15ef2aa78e833531c81e0b277ee13bdd409efb3b3989a4b06366c98bb1c67b1f' 
  AND token = 'bi8uOQx0o4D5HCX3h+LifS39D9KWUXDIjxCLZuvAMcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}