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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c74392415a678a4327ad1755887c7e81a8e886f7dffe09daf0626eeea5d9842' 
  AND token = '4v1zYEuEwjTZsbRY7XWMIPfIRSCsce2E2LteCvOlAlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}