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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b796fde16dc230ba1f95f4a69d2c27a4e60852025f4e70d3ad0a463028ee49a4' 
  AND token = 'FJr3wNHK0I9/F8OvwJP0dP0kiDg1FZTHZugdsbRpqoQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}