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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '34721ad97d89dd55b82287c4dc9ee10d277ec464b337f8889b4ff3e17c9a2c90' 
  AND token = 'nplrIurpXsld4zPmtTzF65M/ijyJ5hfYDYFUkH66QsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}