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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '272e3732ca87bcd28e78d4f82ef91c7361d602d828b743595e30dde5325b51a1' 
  AND token = 'XLhaWymf5qCY4LDjZRjPHD08Ls1Cg6cWfY/t2EvXkuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}