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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95c8f08f70631cbca7ad8a84d7f505ec28c65946f8b53b55707a0e01f8f38839' 
  AND token = 'Ic7JAXk9DDPHhSD7LwBWnv8hfbf4JdFcg2nV3lthNW0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}