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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '046909c120ec43436c658c3a5165d4cc8c272f99ce042ba1fd238c3d86a0621f' 
  AND token = 'g/n4ZEq9u4luokghV5UW0neW5kmg/SijwVz9phOB/k8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}