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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cce89a76bf6ee64818188dd6bfb7683911c03dc140bde8172d97167aa2fc98f' 
  AND token = 'G1uzkK0YFvIAyaGSmRoMd4gIrlXjQabygs5vFOsJLxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}