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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f49cda5efdb1a5ff2964b34eba81e0a40f73c79963606ea336c20b544b35f583' 
  AND token = 'E+o+0WnEqV0kQJwoAwx/uLerafzR4G/B9O+TLl092VI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}