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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b50a4236dca640f2555819f53af1cdef317c2901e493b7f76119a4eee335f99d' 
  AND token = 'olhFBNUY3x7OEYDJVAOr0TMAq9xIO3FWuC5uRFvi4Zk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}