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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a154426410ed2820f99d562ea5c888e16a0cd81e697b6415a1d8925df03b0d7' 
  AND token = 'Dwr1SRK6BtK3vp8myvpwBsnLvEGnok2inGo2mnILid0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}