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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b4cf9ff2bf72e7eeb9342d8942e18a20ed14ebf9de05032725e57e998412495' 
  AND token = 'h/NKkbJfOXKJvhZkoore2gjW2okO1xb95tZejQrkdjc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}