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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ed18cb9954df4a25a5a74f2d85b882619c0944e9f8b57fb07507fa17cffacfa' 
  AND token = 'dwIBcpX9nVm7EVt+SFIxbGoaR8WMcoK61YnDzxcP8W8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}