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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'def9be23c607e88f2f5fd23f2f2b3d44e9847299ff44826cf436489f901c00f3' 
  AND token = '00BsCX/hMn5AxOhKvOZ6awOKyxpPReQzf4BYJObYaF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}