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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e322a53afdc3abedacd2acbfc7490cacb04ccad78755558e62f0f54defda2fe' 
  AND token = 'oSdKRWo+2D7kPCeL/g1h0QGFr5KOPk32JPAveYU1pw4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}