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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd539a26a04ffab5a2c72f8b8ba9182a34f9c75053f345e21f0e5cc3623b3513' 
  AND token = '2zAPv1cK9ep/IJxUZ/ncEcTyFS6zlltW9cWMXq2U8UQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}