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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60ff66dcb5f947509c79808677efdeb64e30cbbdf44df30738614c44ffbe506c' 
  AND token = 'ChbMbVTfMLGSfC8vzU4V/l8lmnzhPOvIBPN/W0I0Oa8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}