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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4153ec389f32d8e8a1e1d1d2ee8218274e96f08ab772f1e3c28a830e40a2a0f5' 
  AND token = 'JiJOQIcYUtSoStOL10gsxbM7oXk09TGy47FftKAE7RE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}