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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc0b0218269882ed9dd1ce67430ef6d0d13789d4ebfc3e3a97954d629f64475d' 
  AND token = 'cEItFx55qflAytNk4LNkxJmy5DC2M5Erek0bAX4av2E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}