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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '420c6b54831f7a54f69ccb9e1b1cbfdf9fa2defb135bf70f14a0aa532564ee1a' 
  AND token = 'GZ2mEtvRZJL5cYHxOt8eRW24ZpHR0OjLbim6qCEHAWs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}