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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '526a3aa146633fdbbdee7071fa1be4e48eea56c0077af3b69a6c7f428e859a11' 
  AND token = 'Id1OedAd+Ecxh8gqAGdL4QmS7UMNW90pOpF8a4u7oCE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}