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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7be7fd3746db1e4d0da81561ed5da622d010a2e25347c4ebda8738e41bf1504e' 
  AND token = 'polVorCN4G+fFPSmUKEh1bYtPkuD19nz8uV6jZ+U3fE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}