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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c1acb2e976ad39277477db3078c9cbb4b6290c536e8d55a2a7c395e31128a1c' 
  AND token = 'T6mJ6CeiUTXhs6TLRVf3+WzzWjO2ph6GRBeY/OdASa8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}