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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '594394cf0fa732ad62098aa2a4f6700e46dd7a23c095f1cc3bb0bac00d353358' 
  AND token = 'CtU/CUkcbAQB43ml/qHfAjKHuITwYJkP9Tk/vAyXKAU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}