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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1acaf888f8462def51eef8a08ac464297fc12af4b31f3bbaa7b38cfb7df1b80b' 
  AND token = 'OKu99eOo6Ub21SxsHx5pt1RfGy7H0VUYJ7uoPCUilVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}