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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8efa46d5506ba194c4f46cb9d7a2e0bd8a428085caca7f67c4ebd3625d9c2bcd' 
  AND token = '16MYo7m1+wqsnz7A7TADxPLaVFroKvCzasfxPUSf1gQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}