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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c287a45f1bed2d70376f0e29b46f643795f7137e7f077c0163dc24fc5084ecbd' 
  AND token = 'TMuY6rv/l1410wL/KFGEONVvfwQ8ExcM/cm2cEuxg3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}