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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65f61c1f99021165989f989c4e0c8fce613cd4b4909163e6609b71a427c15b7d' 
  AND token = '31JEEUjE+Mpii/HwOre5IH2QvGfgFdkgDJEhl1CRJUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}