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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '990423463899d8d3a70a32767e2ab171d1850d92672512fd41310ed1454ba674' 
  AND token = 'wiMOE+Rf3i3mQ0mK6io/NorlZhBy3V0dQtLCpR2W4C8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}