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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '60069111ef76b792d3a3232e1991e84bde0c9f39a16f0be475d991dc95994b17' 
  AND token = 'PR/ei66ID4Y5Xefy9yvWXT6C5USq9EXTsDZnOtYhKSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}