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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d3be40f341a711d19fc51fa2062ee91c9e05cdae38a05e7991906c5a5756f16' 
  AND token = 'xPPSpmXpxmfo/0rDP+A7R54K47B76l4mqpFR8vASVDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}