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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6eaa8b857931b4e4ffb3829b89b848b6014f35692723176e692b0e7fa10376da' 
  AND token = 'OKGwkAdezs5bCZ1ZtfN3z8AU/CNBFVTeY44HWjU4xT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}