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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '429c05e664770f9c7d7f494f41c131e1aae9c5262da5e9f5bbb3161764330818' 
  AND token = '/G8XF4AFn7NhjPenuk7tA1mtbHYolv5ZriHghyGPNMI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}