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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2fe48b4639b41a619d44da928c0c19b4f011444a8007595d60418324c26dc8f' 
  AND token = '+1oj/Y+l7KGAqtXG6GSbip/edMhO+ySApXHFyRqyrHo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}