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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4337e0565c289a1530ca4ee96060d221a218c051c5c145b787c77e6db911f39' 
  AND token = 'mT3hMWAy5A2P1kkw43b6COVYyMT5FokFxqIxkytkFRI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}