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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e07a6d011db967a636ad71f3d4606ebe94a78b8f91d89ca50a133e510362193d' 
  AND token = 'Yy6fmExF6nzRrbxN3Y0daLo5xwrqZ8NWmIsjGTHVEgY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}