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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '634b73b48710ff7512f03b7f14f78364bf8f1a6f6a6e62a1ac14000af5b6bc78' 
  AND token = 'YDuXaIx/xDsOfzAt+v+dhy+hGa8yfFWrV4QcsT1dQ0o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}