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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ef979fefa4c87c3b09e7a309f8671a742f687ed43c583ba972144288042c132' 
  AND token = 'QScW1uYaQIXHP3KbEfh7aJewOpzYnvhN1sNrthZm9k0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}