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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eeee3a5cd3efefd96e3047e5f22145f80b539201be1648d45232e02e0b634317' 
  AND token = '6ojiCp22RmWcSwiSI+DTDEPc/FsYo0sv5a7WkhHoCes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}