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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '416c1394cce2614db8c0a2d908abb4f780c8bc76fbffed1ca1602ec738da8cb9' 
  AND token = '68PD6P7YcNrpQ9stdT/fisxAVcgqcwfRPAiLzpKtrjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}