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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff68df62f9b631e5a48b32595b0f03baee33b38624bce77ed18e7e80f5a5109c' 
  AND token = 'Y7+1EoZLuXKY6FkEw0fsQr9LS5nxZHihahQ3fsd//8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}