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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd030690139ad55bd7e8e37d10b7d44df216d0e7cc66ca811a2184544e2e71a38' 
  AND token = 'QrvO4dFAnlsDol9brBt+OOb1SybjKZ1N7wONr6Ad6Dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}